S72-2 The Ovarian Inositol Phosphate Cascade and Fertility

Program: Symposia
Session: S72-Novel Signaling in the Ovary
Supported by Found Animals Foundation, Inc.
Tuesday, June 18, 2013: 7:30 AM-9:00 AM
Presentation Start Time: 8:00 AM
Room 206 (Moscone Center)
Mario Ascoli*
Univ of Iowa, Carver College of Medicine, Iowa City, IA
Talk Description:

Mice with a granulosa cell specific deletion the G protein alpha subunits that activate phospholipase C are infertile because of a defect in follicular rupture which is likely mediated by a defect in the increased expression of the progesterone receptor that occurs prior to ovulation.

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