S62-2 PCOS and the Risk of Cardiovascular Disease

Program: Symposia
Session: S62-Long-Term Health Consequences of PCOS
Clinical
Monday, June 17, 2013: 4:00 PM-5:30 PM
Presentation Start Time: 4:30 PM
Room 102 (Moscone Center)
Evelyn O Talbott*
Univ of Pittsburgh, Pittsburgh, PA
Talk Description:

Polycystic Ovary Syndrome (PCOS) is a reproductive endocrine disorder characterized by chronic anovulation and hyperandrogenism affecting approximately 5-10% of the female population (Knochenhauer, 1998). Several dimensions of this syndrome, including insulin resistance, obesity, dyslipidemia, and impaired glucose tolerance (IGT), may significantly arbitrate cardiovascular disease risk in this unique female population. This presentation will review the results of studies of both subclinical and clinical cardiovascular endpoints in women with PCOS. These include investigations which have included measures of subclinical atherosclerosis including coronary artery and aortic calcification, carotid intima-media wall thickness, and endothelial function in PCOS cases and controls. Finally, we will consider the evidence that women with PCOS compared to controls or women without PCOS have exhibited an increase in CHD endpoints. (Myocardial infarction, angina pectoris, coronary angioplasty, etc)