Session: SUN 432-458-Thyroid Autoimmunity
Poster Board SUN-454
Methods: The clinical and laboratory data of 153 patients with HT at presentation and long-term outcome were retrospectively evaluated using patient records.
Results: At diagnosis the patient ages ranged from 2.1 to 16.1 years (median 10.8 years) and female/male ratio was 139/14. The complaint at the time of hospital presentation was goiter in 71.9% of the patients. Other reasons for referral were clinical symptoms of hypothyroidism (2.6%) and findings on work-up for an unrelated problem (20.9%) or for high-risk groups (2.6%). At baseline, 47.1% (n=72) of the patients were euthyroid, whereas 31.4% (n=48) had subclinical hypothyroidism, 14.4% (n=22) of subjects were evaluated as hypothyroid. Out of 153 patients, 11 were diagnosed with hashitoxicosis. From these 153 patients, the analysis was performed to those 133 patients in whom follow-up examinations over at least 6 months were available. Mean follow-up was 3.5 years. Nine of the 58 subjects, who were initially euthyroid developed subclinical or overt hypothyroidism during the follow-up period and were started on thyroid medication.
Conclusions: Thyroid function tests should be repeated periodically to detect progression to hypothyroidism in initially euthyroid patients as well as reversibility of hypothyroidism.
Nothing to Disclose: HSL, JSH
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