Evaluation of carotis intima media thickness in adrenal incidentaloma patients

Program: Abstracts - Orals, Featured Poster Presentations, and Posters
Session: MON 1-36-Adrenal Incidentaloma & Carcinoma
Monday, June 17, 2013: 1:45 PM-3:45 PM
Expo Halls ABC (Moscone Center)

Poster Board MON-7
Rifat Emral*1, Ayla Demir Köse1, Berna Imge Aydogan1, Mustafa Sahin2 and Demet Corapcioglu1
1Ankara University, Faculty of Medicine, Ankara/TURKEY, 2Ankara University, Faculty of Medicine, Ankara/TURKEY, Ankara, Turkey
Background: The prevalence of adrenal incidentaloma in the general population is about 3-4%. Nearly 15% of these are functional and those which secrete steroid hormones especially cortisol and aldosteron can cause acceleration in atherosclerosis. However it is not clear whether nonfunctional adrenal incidentaloma (NFA) increases the risk of atherosclerosis.

Aim: In this prospective study, we aimed to determine the effects of NFA on atherosclerosis.

Method: As the carotid intima media thickness (CIMT) is a valuable marker for evaluation the premature atherosclerosis, we compared CIMT of the 20 patient with NFA (group 1) with 18 healthy controls (group 2).

Results: Mean age of the subjects in group 1 was 53,3±7,0 and in group 2 was 50,27±11,32 years; the groups were matched in case of age, sex and blood pressure. Besides body mass indexes (BMI) and waist circumferences (WC) were not different between groups (BMI were 26,66±4,42 vs 27,48±4,90 kg/m2 in group 1 and in group 2; WC were 93,20±10,20 vs 93,38±9,56 cm in group 1 and group 2). When we compared CIMT values between groups, we found highly significant higher values in patients with NFA (right CIMT were 0,788±0,118 vs 0,532±0,100 and left CIMT were 0,786±0,082 vs 0,522±0,087, in group 1 vs group 2 respectively; p<0,0001).

Discussion: Although our study is limited in case of the study subjects and preliminary, these results are in favour of an accelarated premature atherosclerosis in patients with NFA.

Nothing to Disclose: RE, ADK, BIA, MS, DC

*Please take note of The Endocrine Society's News Embargo Policy at http://www.endo-society.org/endo2013/media.cfm