Pilot Study: Anti-inflammatory Diet and Stress Reduction Techniques to Improve Glucose Control

Program: Abstracts - Orals, Featured Poster Presentations, and Posters
Session: SUN 839-872-Diabetes & Obesity Management
Clinical
Sunday, June 16, 2013: 1:45 PM-3:45 PM
Expo Halls ABC (Moscone Center)

Poster Board SUN-847
Maria Brito*1, Sagarika Nag2, Louann Kuntz3, Sharona Wheeler3, Tammy Colley-Odgen3, Teri Hutson-Mulligan3, Margaret Malone4, Lauren Jacobson5 and Sharon Alger6
1ALBANY MEDICAL CENTER, Albany, NY, 2Albany Medical College, 3Albany Medical Center, 4Albany College of Pharmacy and Health Sciences, 5Albany Medical College, Albany, NY, 6ALBANY MEDICAL CENTER
Objective: To evaluate the effect of an anti-inflammatory diet and stress reduction techniques on quality of life, emotional eating and objective markers of stress.

 Methods: 18 subjects were enrolled in a 6 week lifestyle intervention program including instruction in anti-inflammatory cooking and meal plan, physical activity (30-40 minutes at least 5 times/week), and stress reduction techniques. Heart rate variability, quality of life, psychosocial questionnaires, and cortisol levels were evaluated at baseline and upon completion of the intervention.

 Results: Heart rate variability (coherence) improved significantly during the 6 week intervention (39% pre-intervention vs. 74% post-intervention, p<0.01). Significant improvement was seen in the SF-36 quality of life measurements for the following assessments: Role Limitations of emotional stress (56.6 vs. 83.3, p=0.03), Vitality (48 vs. 54, p=0.04), General Health (61.3 vs. 67.1, p=0.02) and Mental Health component (43.1 vs. 48.4, p=0.037). There was significant improvement in the Beck Depression inventory (10 vs. 5.8, p=0.05) and the Eating Disorder Diagnostic Scale (9.4 vs. 5.9, p=0.02). Salivary cortisols showed a reduction in the morning, noon and evening samples, but only the noon sample reached statistical significance (p=0.04).

 Conclusion: This short term practice of stress reduction and anti-inflammatory diet techniques produced significant improvements in heart rate variability, salivary cortisol levels, emotional eating, depression and overall quality of life among participants, and could represent a simple, cost-effective adjunct to conventional lifestyle modification in managing T2DM.  A larger study is planned to investigate the impact of these techniques on glucose regulation in patients with poorly controlled type 2 DM.

Nothing to Disclose: MB, SN, LK, SW, TC, TH, MM, LJ, SA

*Please take note of The Endocrine Society's News Embargo Policy at http://www.endo-society.org/endo2013/media.cfm