Session: SAT 786-805-Diabetes & Obesity Therapeutics
Bench to Bedside
Poster Board SAT-801
Objectives The primary objective of the study is to determine if three times a week SMS as an adjunct to the standard of diabetes care would improve adherence to diet and exercise. The secondary objective is to determine the mean change in body weight, body mass index (BMI) and glycosylated hemoglobin A1c (HbA1c) among the study subjects in the control and SMS group at the 3rd and 6th month of study.
Methodology This is an open-randomized controlled trial. Total of 104 eligible subjects were randomized into control and SMS group, 52 subjects for each group. The control group received the standard of care for diabetic patients while the SMS group received 3 times a week SMS aside from the standard of care for diabetic patients. The study duration is 6 months. Z test of two proportions was used to determine if there will be significant difference in dietary and exercise adherence between the control and intervention group. Mean change in body weight, body mass index and HbA1c for both control and intervention group is also determined.
Results After 3 months, improvement in adherence to diet and exercise, HbA1c,body weight and BMI is observed in both SMS and control group. The difference in improvement between the two groups is not significant except for the levels of HbA1c (mean + sd: SMS= 7.13 + 0.99 vs control= 7.53 + 0.91, p=0.034). After 6 months, the improvement in adherence to diet and exercise, HbA1c, body weight and BMI in both groups is sustained although significant difference in improvement is only seen in the mean number of meals/day (Mean + sd meals: SMS=2.61 + 0.63 vs control= 2.29 + 0.72, p= 0.018), mean number of minutes/exercise (Mean + sd minutes: SMS= 37.40 + 14.87 vs control=31.44 + 10.82, p= 0.021) and HbA1c levels (Mean + sd: SMS=6.99 + 0.86 vs control= 7.34 + 0.90, p= 0.0452).
Conclusion The use of SMS as an adjunct to the standard of DM care improved adherence to diet after 6 months in terms of mean number of meals, improved adherence to exercise after 6 months in terms of mean number of minutes/exercise and significant reduction in HbA1c levels after 3 and 6 months .
Nothing to Disclose: CAT, ITI, CAJ
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