High Total And Central Body Fat Percentage in Type 2 Diabetes Patients in Pakistan

Program: Abstracts - Orals, Featured Poster Presentations, and Posters
Session: MON 776-795-Cardiometabolic Risk & Vascular Biology
Clinical
Monday, June 17, 2013: 1:45 PM-3:45 PM
Expo Halls ABC (Moscone Center)

Poster Board MON-790
Omar Akhter* and Jaweed Akhter
Aga Khan University, Karachi, Pakistan
High Total And Central Body Fat Percentage in Type 2 Diabetes Patients in Pakistan

Omar Akhter, Faraz Fiazuddin, Ayesha Shaheryar, Warda Niaz, Daniyal Siddiqui, Safia Awan, Jaweed Akhter

Section of Endocrinology, Dept of Medicine, Aga Khan University, Stadium Road, Karachi 74800, Pakistan

Abstract


Type 2 Diabetes Mellitus (DM) rates are increasing rapidly in South Asians.  Cardiovascular complications are more frequent and occur earlier in our patients than patients in many other ethnic groups. Reasons for this are not fully understood. We set out to evaluate the body total and central fat percentage on a group of randomly selected patients with Type 2 DM at our hospital in Karachi, Pakistan. One hundred and seventy five (95 male, 80 female) patients with mean age 54.1 ± 12.0yrs were evaluated. Mean duration of DM was 8.1 yrs, mean HbA1c was 8.1% and 53.7% were on oral agents and rest were on insulin with or without oral agents. Hypertension was present in 65.7%, 13.7% had known coronary artery disease and 2.3% had cerebrovascular disease. Mean BMI in males was 29.1 ±4.74 kg/m2 and in females 31.7 ± 5.3 kg/m2. Mean waist circumference in males was 107.3 ± 16.6 cm and 103.09 ± 12.0 cm in females. Body fat percentage was measured with an Omron Body Fat Analyzer. Total body fat percentage in males was 30.9 ± 7.1% and females 40 ± 8.2% with 89% of the total cohort having total body fat percentage above the normal of less than 25%. Central fat percentage was 13.3 ± 5.2% in males and 14.6 ± 5.5% in females with 79.4% of cohort having increased central fat (normal <9%). Total and central body fat correlated with BMI (r=0.68, p<0.001) and waist circumference (r=0.66, p<0.001) but not with HbA1c, triglyceride level or with fasting or random blood glucose levels. Women had significantly higher total body fat percentage compared to men (p <0.001) although central fat percentage was similar in both sexes. We conclude that high body fat percentage, waist circumference are seen especially in women and central body fat percentage in both sexes among patients with Type 2 DM in Pakistan. Body fat percentage should be measured and followed as this may be an important contributing factor to the high macrovascular complication rate in this part of the world

Nothing to Disclose: OA, JA

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