Young adult patients with adrenal incidentalomas in a group of 2490 cases registered at a single endocrinological center

Program: Abstracts - Orals, Featured Poster Presentations, and Posters
Session: MON 1-36-Adrenal Incidentaloma & Carcinoma
Monday, June 17, 2013: 1:45 PM-3:45 PM
Expo Halls ABC (Moscone Center)

Poster Board MON-5
Anna A Kasperlik-Zaluska1, Andrzej Cichocki2, Maciej Otto3, Jadwiga Slowinska-Srzednicka1, Elzbieta Roslonowska1, Wojciech Jeske1, Piotr Zdunowski*4, Rafal Slapa3 and Wojciech Zgliczynski1
1The Medical Centre of Postgraduate Education, Warsaw, Poland, 2M. Sklodowskiej-Curie Memorial Center of Oncology, Warsaw, Poland, 3Medical University of Warsaw, Warsaw, Poland, 4Bielanski Hospital, Warsaw, Poland
Frequency of ~1% of young adults with adrenal incidentalomas (AI) has been noted in the literature..In our department a significant number of patients with AI has been observed within last ~20 years (1,2). This study aimed at evaluting incidence and character of  AI in young patients, up to 30 years of life, in our group of 2490 cases with AI. 99 (4%) such patients have been noted. 50 patients were treted by surgery. Adrenal cancer was found in 25 patients (50%). Other histopathological opinions:adenoma - 9, cyst - 6, pheochromocytoma 5, and single findings -teratoma, ganglioneuroblastoma, hemangioblastoma, hematoma, nodular hyperplasia. 49 patients have been observed carefully without any distinct progress in the imaging studies. Non classic congenital adrenal hyperplasia was diagnosed in a part of them, with slightly elevated androgens levels and low normal cortisol values.We suppose that ultrasound abdominal screening resulted in a relatively high incidence of  AI (verified by CT) in young patients selected from our material.Conclusions: 1/ AI appeared to be more frequent in our group of young adult patients than it was described in the literature. 2/ AI with oncological indications for surgery were more frequent in the group of young adult patients than among older ones. 3/ Adrenal cancer was more frequent in the group of young adult patients than in whole population of AI (7%).

1.Kasperlik-Zaluska AA, Cichocki A, Otto M et al: Incidentally discovered adrenal tumors: a lesson from observation of 1444 patients . Horm. Metab. Res.2008, 40, 338-341. 2. Kasperlik-Zaluska AA, Cichocki A, Otto M et al: Malignant adrenal incidentalomas registered at a single endocrinological center. Endocr. Abstracts, P79, ICE/ECE 2012, 5-9 May 2012, Florence.

Nothing to Disclose: AAK, AC, MO, JS, ER, WJ, PZ, RS, WZ

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Sources of Research Support: Supported by a CMKP grant no 501-1-08-11-12.