Prevalence and clinical characteristics of diabetes in Korean patients with pancreatic cancer

Program: Abstracts - Orals, Featured Poster Presentations, and Posters
Session: MON 818-841-Diabetes Pathophysiology & Complications
Basic/Clinical
Monday, June 17, 2013: 1:45 PM-3:45 PM
Expo Halls ABC (Moscone Center)

Poster Board MON-839
Hee sun Kwon*1, Eun Chung1, Jang Won Son1, Seong Su Lee1, Sung Rae Kim2 and Soon Jib Yoo1
1The Catholic University of Korea, Bucheon St. Mary’s Hospital, Bucheon, South Korea, 2The Catholic University of Korea, Bucheon St. Mary’s Hospital, bucheon, South Korea
Prevalence and clinical characteristics of diabetes in Korean patients with pancreatic cancer 

Hee sun Kwon, Chung eun, Jang Won Son, Seong Su Lee, Sung Rae Kim, Soon Jib Yoo*

Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea, Bucheon St. Mary’s Hospital, Bucheon, Korea 

This increased prevalence of diabetes in patients with pancreatic cancer (PC) is well established, but the nature of this association is obscure. In this study, we aimed to investigate the prevalence and duration of diabetes in Korean patients with PC and the relationship between the two diseases. A total of 138 patients with primary PC who were diagnosed from September 2007 to September 2012 were enrolled in the study. Among 138 patients with PC, 60 (43%) of the patients had diabetes before diagnosis of PC. The period between the diagnosis of diabetes and detection of PC was over than 5 year in 23 patients and less than 2 year in 19 patients who had previous diabetes, respectively. Recent-onset diabetes was detected in 11 of the PC patients. The prevalence of recent-onset and shortly-before-diagnosed diabetes has been found high in patients with PC. This likely suggests a different mechanism of developing PC in patients with recent onset diabetes. Among diabetes group, 36 (60%) of the patients were treated with oral hypoglycemic agents and 20 (33%) of the patients were treated with insulin. There were no significant differences in the location and stage of tumor and other clinical variables between patients with or without diabetes. In conclusion, as it has been reported in other population, we determined high prevalence of diabetes in PC patients in Korea. PC should be considered in Korean patients with recent onset diabetes.

Nothing to Disclose: HSK, EC, JWS, SSL, SRK, SJY

*Please take note of The Endocrine Society's News Embargo Policy at http://www.endo-society.org/endo2013/media.cfm