Osteoporosis risk factor and BMD measures of postmenopausal women population in Latvia

Program: Abstracts - Orals, Featured Poster Presentations, and Posters
Session: SAT 248-267-Osteoporosis II
Clinical
Saturday, June 15, 2013: 1:45 PM-3:45 PM
Expo Halls ABC (Moscone Center)

Poster Board SAT-253
Inese Pavlina*1, Ingvars Rasa2, Inara Adamsone3, Ilze Daukste4, Sandra Jaundzeikare5, Dainis Kaneps6, Ingrida Kaze5, Agita Medne7 and Signe Zelca5
1Riga East Clinical University Hospital Gailezers, Riga, Latvia, 2Riga East Clinical University Hospital, Riga, Latvia, 3Pauls Stradins Clinical University Hospital, 4Riga 2nd Hospital, 5Riga East Clinical University Hospital, 6Latvian Maritime Medicine Center, 7Health Centre 4
Objective(s): We aimed to assess prevalence of osteoporosis (OP) risk factors,  OP preventive and therapeutic measures among postmenopausal women in Latvia. We also aimed to correlate bone mineral density (BMD) with those OP risk factors in this population.                                    

Material & Methods: We conducted a cross-sectional survey among 1558 randomly selected  community dwelling postmenopausal women, who were referred for DXA scan in several osteoporosis clinics in Riga, Latvia. All women filled out a questionnaire with 25 multiple choice questions regarding  OP risk factors, ie.  fragility fractures, family history of fractures, smoking, physical exercises, glicocorticosteroids use, etc. Previous osteodensitometry, calcium, vitamin D usage and anti-osteoporosis medication were recorded.  BMD was subsequently measured in all participants by DXA in lumbar spine (L1-4) and total hip.

Results: The mean age of patients was 65.6 ±9.0 years,  the mean body weight was 71.9 ±13.7 kg , the mean height was 159 ±6.3 cm, the mean time since menopause was 16.3 ± 3.7 years. Progressively reduced height was recorded in 79.2% of the patients. Previous fragility fractures were recorded in 38.6% patients, 26.8% had a family history of fractures. 8.2% patients smoked, 59.5% had no physical activities. 7.4% of the patients took glicocorticosteroids, of which 69.6% had been taking the medication for more than three months. 63% of participants underwent DXA scan before, in 41.9% of them OP was previously diagnosed. 40.3% of participants measured 25  (OH) vitamin  D before. 66.1% of them had reduced 25 (OH) vitamin D level. 60.7% of the patients used supplemental calcium and 36.2% - vitamin D, 31.3% received specific osteoporosis treatment.BMD measurements in lumbar spine, left and right hip negatively correlated with age (p< 0.001, p< 0.001 and p< 0.001 respectively), positively correlated with body weight (p< 0.001, p< 0.001 and p< 0.001 respectively). The earliest menopause was associated with  lower BMD in lumbar spine (p<0.001).                                                                           

Conclusion(s): This survey suggests that OP is suboptimally diagnosed and undertreated in Latvia and insufficient attention is paid to OP risk factors.The results of this study also suggest that advancing age and lower weight are important risk factors for low BMD in postmenopausal women in Latvia.

Nothing to Disclose: IP, IR, IA, ID, SJ, DK, IK, AM, SZ

*Please take note of The Endocrine Society's News Embargo Policy at http://www.endo-society.org/endo2013/media.cfm