Session: SUN 459-496-Thyroid Neoplasia & Case Reports
Poster Board SUN-473
207 patients, (124 “low”, 77 “intermediate” and 6 “high” risk), were again evaluated after 1 year with whole-body scintigraphy and Tg levels (plus Tg-Ab) after stimulation with Thyrogen or LT4 suspension. Tg was < 1 ng/ml in 174 patients and ≥ 1ng/ml in 33; Tg-Ab levels were positive in 9 patients with Tg <1 ng/ml and in 3 of theese thyroid scan was positive. Patients were considered “not free” from disease if their stimulated-Tg levels were ≥1 ng/ml or if, when Tg-Ab were positive, thyroid scan showed I131 uptake. 17 (13.7%) patients in the “low “ risk group, 15 (19.4%) in the “intermediate” group and 3 (50%) in the “high” risk were “not free” from disease. Of particular interest in the “low” risk group, 3 patients had Tg levels >15 ng/ml and 2 (with positive Tg-Ab) showed I131 uptake at the thyroid scan, thus showing persistence/recurrence of disease. Our data show that a significant percentage of patients in the “low” risk group cannot be considered “free” from disease 1 year after I131ablation; these data suggest that caution is requested in the follow up of “low” risk patients too, and might have implications in the therapeutic goal before TSH-stimulated Tg and whole-body scintigraphy is performed.
Nothing to Disclose: SM, IB, FF, CG, GN, VD, AD
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