Session: SUN 498-523-Female Reproductive Endocrinology & Case Reports
Poster Board SUN-523
All women had at least 1 sign of virilization. Its presence was much more common in women with VOT than in women with OH (alopecia: VOT: 7 of 7 x HO: 4 of 7; clitoromegaly: VOT: 6 of 7 x OH: 1 of 7; deepening of the voice: VOT: 7 of 7 x OH: 1 of 7 and increase muscle mass: VOT: 7 of 7 x HO: 1 of 6). A virilization index (one point for each symptoms and signs) was higher in VOT (3.7±0.7) than in OH (0.8±0.4) (p<0.001).
Testosterone (RIA, median of 2 values) was higher in VOT (516.7±270.2 ng/dL) than in OH (179.5±102.8 ng/dL) (p<0.001), but with overlap between both groups (minimal and maximal values – VOT:184 and 1,114 ng/mL; OH:103 and 503 ng/mL); 4 women with OH has a higher testosterone level higher than the minimal value observed in VOT (185 to 245 ng/mL x 184 ng/dL). DHEAS, D4, 17OPH and LH were not different between the groups (p>0.01), but FSH was significantly lower in VOT (9.8±8.7 IU/L) than in OH (42.1± 17.5 IU/L) (p=0.001). Only 1 woman in the OH group presented a concentration of FSH lower than 33 IU/L (10.5 IU/L), whereas the highest concentration of FSH observed in group VOT group was 23.4 IU/L.
Nothing to Disclose: VDRVY, JAM, CRB, MPR, SD, ECB
*Please take note of The Endocrine Society's News Embargo Policy at http://www.endo-society.org/endo2013/media.cfm
See more of: Abstracts - Orals, Featured Poster Presentations, and Posters