SPONTANEOUS PHYSICAL ACTIVITY, AEROBIC PHYSICAL EXERCISE AND PLASMA ADIPOKINES IN POSTMENOPAUSE

Program: Abstracts - Orals, Featured Poster Presentations, and Posters
Session: SUN 678-689-Adipocyte Biology
Clinical
Sunday, June 16, 2013: 1:45 PM-3:45 PM
Expo Halls ABC (Moscone Center)

Poster Board SUN-684
Andrea Di Blasio1, Sandra Melanzi*1, Ines Bucci2, Marilena Olivieri1, Alessia Sagazio1, Cesidio Giuliani2 and Giorgio Napolitano2
1University of Chieti, Chieti, Italy, 2University of Chieti-Pescara, Chieti, Italy
INTRODUCTION. Aerobic physical exercise has been widely indicated as effective intervention to prevent and treat dismetabolic diseases. Despite several reasons supporting the aerobic training program, literature also report negative behavioural compensations, concerning dietary habits and spontaneous physical activity (SPA), in sedentary person who start training. Aim of the study was to determine whether aerobic physical exercise elicits positive effects on adipokines plasma levels independently from the effects of the training on SPA. METHODS. Thirty-six postmenopausal women (55.94±4.22 yrs), without history of diabetes mellitus, pulmonary, myocardial and orthopedic diseases and without any pharmacological treatment were enrolled and trainined four days per week, for 14 weeks: participants walked at moderate intensity. Aerobic fitness, body composition, plasma values of leptin, adiponectin, resistin, visfatin, glucose and insulin, togheter with plasma lipids profile, were assessed. Daily physical activity (DPA) was objectively recorded through a multisensor device (Bodymedia armband, Sensewear). RESULTS. Despite all of the participants did the same training, three different variations of DPA were recorded (i.e. reduction, increase, no variation) and were used to gather the sample into three sub-groups. Among the three variations, only for the participants that increased their DPA the physical exercise program was an addition; on the contrary, participants who compensated the physical exercise program by reducing their SPA, showed no change or reduction of their DPA. Two-way RM-ANOVA revealed the effect of the training for aerobic fitness (p < 0.001), leptin to FMkg (p = 0.001), resistin to FMkg (p < 0.001) and adiponectin to FMkg (p < 0.001). Visfatin to FMkg seems to have a different trend; indeed there is a quite significant (p = 0.09) group × time effect: the sub-group with no change of DPA showed no variation of visfatin to FMkg, while the reducing and increasing sub-groups had increasing and reducing trends respectively. CONCLUSIONS. Aerobic training increases aerobic fitness and adiponectin to FMkg and reduces leptin to FMkg and resistin to FMkg independently from spontaneous physical activity compensation. On the contrary, visfatin to FMkg modification seems to be influenced by total volume of physical activity instead of physical exercise alone.

Nothing to Disclose: AD, SM, IB, MO, AS, CG, GN

*Please take note of The Endocrine Society's News Embargo Policy at http://www.endo-society.org/endo2013/media.cfm