Session: SAT 677-696-Obesity Physiology & Epidemiology
Poster Board SAT-683
Results: The mean age of the subjects was 32.1 ± 8 years, with an average BMI of 29.2 ± 6.5 Kg/m2 and waist circumference (WC) of 88.5 ± 14.4 cm. Women had higher BMI (p=0.04), waist to hip ratio (WHR) (p<0.001), thigh circumference (TC) (p =0.009), SAT (P<0.001), SAT/VAT ratio (<0.001), and BF% (<0.001). However, men and women did not differ in WC, HOMA-IR, and VAT volume. Mean ADPN levels were 7.2 ± 4.0 ug/mL, with women having significantly higher levels than men (8.4±0.6 vs. 6.5±0.6 ug/mL, p = 0.045). In the overall sample, ADPN correlated negatively with BMI, WC, WHR, VAT, and HOMA-IR. In gender-specific analyses, WHR and HOMA-IR were negatively correlated with ADPN (p < 0.05) in both men and women. ADPN correlated negatively with BMI, WC, WHR, BF%, and VAT (p<0.05) in women, while the same relationships were trending negative but were not statistically significant in men. There was no relationship between SAT and ADPN in men, while a very strong negative relationship was noted in women (r=-0.58, p=0.005). These relationships were tempered when SAT/VAT ratio was used in both men (r=0.27, p=0.16) and women (r=-0.17, p =0.44).
Conclusion: AA women have higher adiponectin levels despite higher BMI and BF% and similar levels of visceral adiposity and insulin resistance comapred to AA men. This may explain better mortality and morbidity rates among AA women compared to men and women of other ethnic origin of comparable obesity.
Nothing to Disclose: EA, SK
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