Session: MON 238-262-Vitamin D Action, Deficiency & Disorders
Bench to Bedside
Poster Board MON-262
YADAV, ABHIJEET, MD; SCHLAUCH, KAREN, MS, PhD; IZUORA, KENNETH, MD, MBA
To compare the prevalence of hypertension (HTN) among ambulatory patients with normal and those with low 25 OH Vitamin D (Vit D) levels.
This is a retrospective chart review looking at all patients who had their Vit D level tested for any reason. Vitamin D deficiency was defined as serum Vit D < 30 ng/ml. Data was collected on Vit D level, age, gender, ethnicity, BMI, diagnosis of HTN or treatment with anti-hypertensive medication, and current smoking status. Data collection is currently on- going.
Out of 243 consecutive patients, 201 (83%) had low Vit D. To determine whether Vit D levels, along with age, gender, ethnicity, smoking, and BMI were effective predictors of HTN, several stepwise logistic regression models were developed based on 139 patients with complete data. We found that age and ethnicity were significant predictors of HTN (p<0.00001 and p<0.05 respectively). Focusing on the ethnic groups, only the African-American subgroup (N=38) had a statistically significant association between HTN and low Vit D (p=0.025).
Our findings so far show a high prevalence of vitamin D deficiency (83%) in our study population. Overall, low Vit D was not a significant predictor for HTN. Age and ethnicity were significant predictors of HTN and among all patients, African American patients with low Vit D had the highest prevalence for HTN.
Nothing to Disclose: AY, KS, KEI
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