Session: SAT 806-823-Gestational Diabetes
Poster Board SAT-812
Method: We analyzed 30 pregnant women with gestational diabetes and 38 body mass index (BMI)-matched women with healthy pregnancies as controls. MPV and platelet counts were recorded in the 3rd trimester in both groups and at postpartum 6-12. months in the gestational diabetes group. Fasting plasma glucose and fetal birth weight data were obtained and oral glucose tolerance test glucose area under the curve (AUC) was calculated.
Results: Third trimester MPV was significantly higher in the gestational diabetes group than the control group (8.8±1.0 vs 8.1±0.7 fl, p=0.002). In women with gestational diabetes, there was a significant decrease in MPV in the postpartum period (8.8±1.0 vs 8.1±0.8 fl, p<0.001). Fasting plasma glucose levels (r=0.346, p=0.007) and glucose AUC (r=0.346, p=0.02) were positively correlated with the 3rd trimester MPV. In gestational diabetes group, MPV was not correlated with pre-pregnancy BMI (p=0.119) or fetal birth weight (p=0.304).
Conclusion: Our results indicate that MPV is increased in gestational diabetes and is associated with hyperglycemia. Further research is warranted in this area.
Nothing to Disclose: OT, CK, FT, MA, MA
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