Effect of Self-Perceived Motion on Gait Alteration in People with Type Two Diabetes

Program: Abstracts - Orals, Featured Poster Presentations, and Posters
Session: SAT 786-805-Diabetes & Obesity Therapeutics
Bench to Bedside
Saturday, June 15, 2013: 1:45 PM-3:45 PM
Expo Halls ABC (Moscone Center)

Poster Board SAT-799
Chun-Kai Huang, Vijay Shivaswamy*, Lynn Renee Mack and Ka-Chun Siu
University of Nebraska Medical Center, Omaha, NE
Background People with more than 20 years of diabetes mellitus (DM) are at a high risk of suffering from diabetic neuropathy. Such populations have abnormal sensation of their feet and sensory loss, which increases the incidence of fall injuries during walking. In order to reduce fall incident, our sensory system including visual perception, somatosensory and vestibular sensation is well integrated in healthy people. However, it is unclear how sensory integration is affected by DM. Our previous study indicated perceived motion information presented by virtual environment (VE) did not show the prominent role on gait alteration in healthy adults during treadmill walking. For people with DM, we hypothesize their gait characteristics might differ significantly when VE-induced perceived motion information is present. The purpose of this study was to investigate how the self-perceived motion information of VE impacts Type 2 DM’s gait during treadmill walking. Methods Three participants with Type 2 DM (mean age= 58.7 ± 6.0 years; BMI = 30.97 ± 4.57) who did not show any symptom of neuropathy first walked on a treadmill for a five-minute familiarization. Then they walked on the treadmill with their self-selected pace for two minutes in two different conditions: 1. in a static VR (with a fixed virtual corridor image projected in front of participants); 2. in a dynamic VR (with a moving virtual corridor at a speed corresponding to participant’s self-selected pace. The kinematic data of leg and foot were collected by 3D motion analysis system and processed to calculate all spatiotemporal gait measures. All participants were given a seven-scale Presence Questionnaire to test their self-immersion to the VE. Paired-t test was applied to exam the effect of VE on the gait measures. The alpha level was set as 0.05. Results The Presence Questionnaire score with 6.33 ± 0.58 (out of seven) showed that all participants had a strong self-immersion in the VE during treadmill walking. Self-perceived motion significantly impacted gait by decreasing average step length (p= 0.02) and the coefficient of variation of stride time (p= 0.03) when compared conditions between with and without presenting the motion information from the VE. Conclusions The results support our hypothesis of different gait patterns exhibited due to the present of perceived motion information. Type 2 DM adults without neuropathy modulated their spatiotemporal gait characteristics with respect to the VE. It could imply that a more prominent role of visual information was adopted by the non-symptomatic Type 2 DM than by healthy adults. The significant effect of VE on reduced temporal gait variability also shows an increase in stability during treadmill walking. More participants with DM patients with and without diabetic neuropathy are warranted to confirm the speculation of the effect of perceived motion information on gait alteration in Type 2 DM.

Nothing to Disclose: CKH, VS, LRM, KCS

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