PREDICTIVE FACTORS FOR THE NEED OF INSULIN TREATMENT IN WOMEN WITH GESTATIONAL DIABETES

Program: Abstracts - Orals, Featured Poster Presentations, and Posters
Session: SAT 806-823-Gestational Diabetes
Basic/Clinical
Saturday, June 15, 2013: 1:45 PM-3:45 PM
Expo Halls ABC (Moscone Center)

Poster Board SAT-814
Sandra Belo*1, Angela Magalhães1, Cristina Gamboa2, Joana Queiros3 and Davide Carvalho4
1Serviço de Endocrinologia, Diabetes e Metabolismo, Centro Hospitalar de São João, 2Serviço de Obstetrícia, Centro Hospitalar de São João, 3Hosp Sao Joao-Oporto Med Schl, Oporto, Portugal, 4São João Hospital, Faculty of Medicine, University of Porto, Portugal, Portugal
Introduction:Glycemic control in women with gestational diabetes (GD) can be attained traditionally with diet planning alone or with insulin.

Aim:To evaluate demographic and anthropometric characteristics associated with increased risk the need of insulin treatment for GD.

Methods:This study included women diagnosed with GD between 2011 and the first quarter of 2012. Diagnois was made according to IADPSG criteria. Data related to demographic, anthropometric, analytical and therapeutic parameters, previous to pregnancy and at the beginning of follow-up, were collected.

Results: There were included 176 women with GD, only 113 with complete information regarding anthropometric, analytical and therapy parameters at the beginning of follow-up. Mean age at the beginning of the following was 32.1±5.4 years and mean pre-pregnancy body mass index was 27.6±5.8 Kg/m2. Mean A1c levels at the beginning of follow-up were 4.8±0.5%. Gestational diabetes diagnosis was made by fasting glycemia in 51.3% of the patients and after OGTT in 45.1% of the cases. Glycemic control was achieved only with diet planning in 31.0% of the cases; treatment with insulin was needed in 61.1% of the patients. Insulin therapy was begun at 26.5±7.3 weeks (at 22.7±7.1 weeks when the diagnosis was made in the 1st T and at 30.3±4.6 weeks when the diagnosis was made in the 2nd T; p<0,001). Women who need insulin during pregnancy presented higher pre-pregnancy body mass index (28.9±6.1 vs 25.0±4.5 kg/m2; p=0.004) and A1c levels (4.8±0.5 vs 4.6±0.6%; p=0.045). No other differences were found namely regarding age, educational level and week of GD diagnosis.

Discussion: Pre-pregnancy body mass index and A1c levels seem to be the major risk factors for insulin treatment in women with gestational diabetes in our population.

Nothing to Disclose: SB, AM, CG, JQ, DC

*Please take note of The Endocrine Society's News Embargo Policy at http://www.endo-society.org/endo2013/media.cfm