Richard S Legro, M.D.

Professor
Penn State Univ, College of Med, MS Hershey Medical Center
Obstetrics and Gynecology

Biographical Sketch:
Dr. Richard S. Legro received his medical degree from the Mount Sinai School of Medicine in New York, NY, completed his residency in Obstetrics and Gynecology at Magee Womens Hospital at the University of Pittsburgh in Pittsburgh, PA and a fellowship in Reproductive Endocrinology and Infertility at the University of Southern California in Los Angeles. He is a Professor in the Department of Obstetrics and Gynecology at Penn State University College of Medicine in Hershey, PA. His research and clinical practice are primarily focused on polycystic ovary syndrome (PCOS)- diagnosis, treatment, and genetic/environmental causes. He established at M.S. Hershey Medical Center one of the first clinics devoted to the treatment of women with PCOS. Dr. Legro has published extensively on phenotype and genotype in PCOS and is part of a NIH funded ongoing Genome Wide Association Study. Dr. Legro is the lead investigator of the multi-center NIH sponsored trials Pregnancy in Polycystic Ovary Syndrome I, a double blind study of metformin and clomiphene and the ongoing follow up Pregnancy in Polycystic Ovary Syndrome II, a double blind study of clomiphene and letrozole. He is additional the principal investigator of a another NIH multi-center trial examining the effects of a lifestyle intervention compared to a control intervention of the oral contraceptive pill prior to infertility treatment, a study known as OWL-PCOS. He has published over 200 articles in medical journals and books in the field of reproductive endocrinology. He has served as a member of multiple NIH study sections. He is an Associate Editor for the journals Human Reproduction and Fertility and Sterility, and is on the editorial boards of Endocrine Reviews, the Journal of Clinical Endocrinology and Metabolism, and Seminars in Reproductive Endocrinology.
Papers:
Smoking and Infertility in Women with Polycystic Ovary Syndrome: Validation of Baseline Self Report and Stability Over Time with Serum Cotinine Levels
CP1 Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline