Andrew James Brooks, PHD

Institute for Molecular Bioscience, The University of Queensland
Division of Molecular Cell Biology

Biographical Sketch:
Dr Andrew Brooks is a Senior Research Officer at the Institute for Molecular Biology (University of Queensland, Australia) and joined the research group headed by Prof Michael Waters in 2006. Andrew completed his PhD in 2002 on the nuclear localization of Dengue virus proteins at James Cook University, Australia. He then moved to St Jude Children’s Research Hospital in Memphis, TN, USA where he researched the role of Epstein-Barr Virus in oncogenesis. Andrew’s research interests are in cell signalling, oncogenesis, and virology. He is currently investigating the molecular mechanism of Growth Hormone mediated signalling via the Growth Hormone Receptor (GHR), the role of GHR in oncogenesis, and the role of GHR signalling in liver regeneration. He also has several collaborative projects including investigating the mechanisms of melanoma metastasis and hair follicle development with A/Prof Kiarash Khosrotehrani’s group (UQCCR, UQ), the physiological roles of caveolae with Prof Rob Parton’s group (IMB, UQ), the development of small molecule inhibitors of GHR signalling with the groups headed by Prof Matt Cooper (IMB, UQ) and Prof Kirill Alexandrov (IMB, UQ), and the mechanisms of IL-10 induction in urinary tract infections with Dr Glen Ulett (Griffith University). In the last 5 years Andrew has published in journals including Nature Cell Biology, PNAS, Molecular Endocrinology, J Immunol, and Nature Reviews Endocrinology. Andrew is a chief investigator on three NHMRC project grants with Prof Waters and was previously awarded a UQ Early Career Researcher grant for the establishment of a retroviral and lentiviral system to delivery genes to specific somatic cell types in mice. Andrew is member of the editorial board of the journal JAK-STAT. He is part of the IMB Science Ambassador Program, and is a committee member for the Australian Early and Mid-Career Researchers Forum, an initiative launched by the Australian Academy of Science.
S04 GH at the Cutting Edge
S04-1 GH Receptor Dynamics Leading to JAK2 Signaling