Associate Professor of Medicine
Brigham & Women's Hosp/Harvard Medical School
Division of Endocrinology, Diabetes and Hypertension
Biographical Sketch: Gail K. Adler, M.D., Ph.D., F.A.H.A. is Associate Professor of Medicine at Harvard Medical School and Associate Clinical Research Center Director of the Harvard Catalyst Clinical Research Center at Brigham and Women’s Hospital. Her research focuses on hormonal mechanisms of cardiovascular disease with an emphasis on the role of the adrenal steroid aldosterone in the pathophysiology of cardiovascular and renovascular disease in obesity, diabetes and hypertension. Through patient-oriented and basic studies, Dr. Adler has demonstrated an important role for aldosterone and mineralocorticoid receptor activation in the pathophysiology of vascular injury, insulin resistance and inflammation. Current studies are investigating the influence of mineralocorticoid receptor blockade on coronary vascular function in humans with type 2 diabetes. Additional studies focus on hypoglycemia-induced alterations in cardiovascular autonomic function and aldosterone in humans. Dr. Adler has a longstanding commitment to mentoring junior investigators in translational research and is Associate Program Director of a T32 Training Grant in Hypertension. She is also a permanent member of the National Institutes of Health Hypertension and Microcirculation Study Section and has served on the editorial boards of both Endocrinology and JCEM. Dr. Adler has published over ninety original reports, reviews and chapters.
Human interventions to assess the physiologic relationship between the renin-angiotensin-aldosterone system and parathyroid hormone
Inside and Out: Aldosterone Synthesis and Action
Aldosterone and its Direct Cardiovascular Damages