L2-1 Neurosteroid Estrogens: Implications for Epilepsy

Program: Plenary
Session: L2-Thursday Afternoon Plenary
Basic
Catherine S Woolley, PhD
Northwestern University, Evanston, IL
Talk Description:

There is growing awareness that estrogens may be produced in the brain as neurosteroids that act locally within specific brain regions to modulate neurophysiology on a time scale of minutes. This lecture will review key findings on acute estrogen actions in the hippocampus, a limbic brain structure commonly involved in temporal lobe epilepsy, and will present pre-clinical evidence of a link between neurosteroid estrogens and the severity of limbic seizures in both sexes.

Nothing to Disclose: CSW
See more of: Thursday Afternoon Plenary
See more of: Plenary