L5-2 The Wiring Diagram for Hunger: Using Neuron-Specific Tools to Discover its Basis

Program: Plenary
Session: L5-Saturday Morning Plenary
Supported by Novo Nordisk, Inc.
Bradford Barr Lowell, MD, PHD
Beth Israel Deaconess Med Ctr, Boston, MA
Talk Description:

Efforts to elucidate neural circuits regulating hunger have been stymied by the complexity of brain interconnections. With recently developed circuit-specific approaches, this complexity can now be “solved”. We are using optogenetics, chemogenetics and monosynaptic rabies mapping, rendered cell-specific by lines of mice expressing cre-recombinase, to map synaptic connections between neurons and to probe function of identified neural circuits. The ultimate goal is to uncover the neurobiological basis, i.e. the wiring diagram, for hunger and satiety.

Nothing to Disclose: BBL
See more of: Saturday Morning Plenary
See more of: Plenary
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