Room 33 (San Diego Convention Center)
**This session is eligible for CME credit**
Andrzej Bartke, Southern Illinois University School of Medicine, Springfield, IL
Raul M. Luque, PhD, University of Córdoba; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)/Hospital Universitario Reina Sofia, and CIBER de la Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Nothing to Disclose: AB, RML Disclosure Not Provided: SM
Besides their role in the control of growth, GH and IGF are endowed with very relevant, tissue-specific actions, whose physiological relevance in terms of metabolic control and longevity is yet to be elucidated. In this session, translational research using suitable genetically modified mouse models will be presented, addressing the impact of tissue-specific elimination of GH actions or adult-onset GH deficiency on metabolic homeostasis. In addition, genetic and molecular studies addressing the roles of the GH/IGF1 pathway in human longevity will be discussed.
Disclosure: RDK: Jose Cordoba-Chacon, PhD was intergral in performing and interpretin many of the studies to be discussed. He has recieved a post-doctoral research award (Endocrine Scholar Award for GH Research 2014) from Genetech, Genentech, Inc..
Disclosure: NB: Founder, CohBar Inc..