S54 RNA Binding Protein in Post Transcriptional Regulation

Program: Symposia
Basic Session
Saturday, March 7, 2015: 9:30 AM-11:00 AM
Room 23 (San Diego Convention Center)
**This session is eligible for CME credit**

Pamela L Mellon, PhD, University of California, San Diego, , CA

Nothing to Disclose: PLM

Mechanisms of regulation of gene expression that are dependent on transcriptional activators, such as nuclear receptors, binding regulatory regions of genes, recruiting co-regulators, modifying the chromatin and initiating transcription have been elucidated in great detail over the past 20 years. Less well described are post-transcriptional mechanisms. RNA binding proteins that bind 5’ and 3’UTR regions of transcripts and influence RNA stability and/or translation are increasingly being shown to play a role in regulating gene expression in a fashion not dissimilar to the DNA binding proteins. This session will explore the role of RNA binding proteins and their relationship to nuclear receptors and steroid hormone action.

9:30 AM
Michael G Rosenfeld, MD, Dept of Medicine, Univ of California - San Diego, La Jolla, CA
Disclosure Not Provided: MGR
10:00 AM
Alberto R Kornblihtt, PhD, Facultad de Ciencias Exactas y Naturales - UBA, IFIBYNE-CONICET, Buenos Aires, Argentina
Nothing to Disclose: ARK
10:30 AM
Nicholas J Webster, MA, PhD, Department of Medicine, Univ of California San Diego, La Jolla, CA
Nothing to Disclose: NJW
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