Session: SAT 270-310-Thyroid Neoplasia (posters)
Poster Board SAT 280
Two hundred four biopsied nodules were graded 0, 1, 2, or 3 on the basis of their abundances of BAFC: 0, acellular [41 nodules]; 1, hypocellular [70 nodules]; 2, normocellular [84 nodules]; 3, hypercellular [9 nodules]. The length of the intra-thyroidal tissue track that the FNA needle traversed to reach the biopsied nodule was measured ultrasonographically [needle tracks ranged from 0 mm to 29 mm]. Nodules diagnosed as “malignant,” “suspicious for malignancy ”or “lymphocytic” were not included among the 204 graded nodules since the relative abundance of BAFC in their FNA samples would not be clinically important and not routinely reported by the cytologist. The biopsies of almost all nodules involved 6 punctures; none less than 4 punctures.
When the BAFC abundance grade for each nodule was plotted against the nodule’s depth within the thyroid, there was essentially no correlation between BAFC abundance and the length of the pre-nodular thyroid tissue needle tracks (Coefficient of Correlation [r] = -0.08). The lack of correlation was equally evident when nodules biopsied with 25 gauge needles [163 nodules] were compared to biopsies using 23 gauge needles [41 nodules].
These results confirm that the abundances of benign-appearing follicular cells in FNA samples represent cells predominantly derived from the thyroid nodules and little if any from the pre-nodular thyroid tissue.
Nothing to Disclose: SS, VN, AG, DK, IJ, CPB
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