Session: SAT 270-310-Thyroid Neoplasia (posters)
Poster Board SAT 279
Method: Retrospective study of 1087 thyroid nodules with benign cytology from 2005 to 2012 was conducted. The information about the rate of surgery in all nodules and the rate of growth in nodules with a follow up period for 36 months or longer was obtained. Growth was defined as minimum of 50% increase in volume or 20% increase in two dimensions of the nodule6.
Result: 360 nodules were followed for at least 36 months (mean: 64; range: 36 to 144). Growth was identified in 74 (20%) of them and surgery was performed in 30 (8%). The rate of surgery was 24% in nodules with growth and 4% in nodules without growth. 1 malignancy (papillary thyroid carcinoma) was identified in a nodule without growth 36 months after initial FNA. The rate of repeat FNA was 61% in nodules with growth and 20% in nodules without growth. The result of repeat FNA was suspicious for papillary thyroid carcinoma in 2 nodules. Both nodules had remained stable during the course of follow up. Rate of surgery for nodules followed for less than 36 months was higher (20%) and the surgery was done mostly due to the large size of the nodule, compressive symptoms or for a cytology result other than benign for another nodule in the same patient. In this group, 2 additional malignancies (papillary thyroid carcinoma) were identified after surgery.
Conclusion: Repeat investigation of asymptomatic benign thyroid nodules based solely on their growth may lead to increased rate of surgeries and repeat FNA biopsies without any significant additional benefit for diagnosis of missed malignancies.
Nothing to Disclose: SH, LS, MSTT, MS
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