Session: SAT 270-310-Thyroid Neoplasia (posters)
Poster Board SAT 278
Methods and Results: An observational study in a personalized fashion of 756 patients, 611 (80.82%) Females and 145 (19.18%) Males, stratified by age groups as follows: 18-39.9, 40-59.9, 60 and older, who underwent standard Clinical and Laboratory care, Ultrasound (ATA criteria) and Fine Needle Aspiration Biopsy (pathology report according to Bethesda classification) was conducted at a general Endocrine Clinic of North Central Florida. The question of drinking underground/well water was also posed. 229 (57.68%), out of 397 surveyed patients, responded positively to the question.
On the Ultrasound findings nodules were located on both right and left sides, had an increased Doppler flow, and well defined margins. Microcalcification, Echogenicity, majority of nodules were hypoechoic, and heterogeneous/cyst. Average dimensions in centimeters of the right nodule were 1.36 (SAG) by 1.08 (TRV) by 1.05 (AP), and left nodule 1.49 (SAG) by 1.19 (TRV) by 1.2 (AP).
There were 53 females between ages of 18-39.9. Biopsy of their nodules showed result of 68.33% benign, 16.67% AUS/FLUSA, 1.67% follicular neoplasm, and 3.33% suspicious or malignant. Nodules of 4 males between ages of 18-39.9, were 50% benign, and 50% AUS/FLUSA. Out of 196 females, ages 40-59.9, nodules were 78.7% benign, 7.92% AUS/FLUSA, 1.49% follicular neoplasm, and 3.47% suspicious or malignant. Nodules of 44 males ages 40-59.9 were 77.77% benign, and 11% AUS/FLUSA. Out of 328 females ages 60 and older, nodules were 75.39% benign, 7.79% AUS/FLUSA, 2.18% follicular neoplasm, and 1.25% suspicious or malignant. Nodules of 89 males, ages 60 and older, were 66.27% benign, 9.64% AUS/FLUSA, 1.2% follicular neoplasm, and 2.4% suspicious or malignant.
Conclusions: The results of this study show that a significant number of patients who developed thyroid nodules responded positively to the question of drinking underground/well water. Based on these results, further research that investigates the correlation, and thus, the possible role that underground/well water plays in the development of thyroid nodules should be conducted.
Nothing to Disclose: AV, RWM, KK, NFR, EJL, KGK, JAG, CCS, HJ
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